Ethyl 2-chloro-1,3-oxazole-4-carboxylate

Ethyl 2-chloro-1,3-oxazole-4-carboxylate - Names and Identifiers

Name	ethyl 2-chlorooxazole-4-carboxylate
Synonyms	Ethyl 2-chlorooxazole-4-c... ethyl 2-chlorooxazole-4-carboxylate ETHYL 2-CHLOROOXAZOLE-4-CARBOXYLATE 2-CHLOROOXAZOLE-4-CARBOXYLIC ACID ETHYL ethyl 2-chloro-1,3-oxazole-4-carboxylate Ethyl 2-chloro-1,3-oxazole-4-carboxylate 2-CHLOROOXAZOLE-4-CARBOXYLIC ACID ETHYL ESTER 2-Chloro-oxazole-4-carboxylic acid ethyl ester 4-Oxazolecarboxylic acid, 2-chloro-, ethyl ester 2-Chloro-1,3-Oxazole-4-Carboxylic Acid Ethylester
CAS	460081-18-9
InChI	InChI=1/C6H6ClNO3/c1-2-10-5(9)4-3-11-6(7)8-4/h3H,2H2,1H3

Ethyl 2-chloro-1,3-oxazole-4-carboxylate - Physico-chemical Properties

Molecular Formula	C6H6ClNO3
Molar Mass	175.57
Density	1.332±0.06 g/cm3(Predicted)
Melting Point	97-98℃
Boling Point	254.1±32.0 °C(Predicted)
Flash Point	107.5°C
Vapor Presure	0.0176mmHg at 25°C
pKa	-3.20±0.10(Predicted)
Storage Condition	Inert atmosphere,Store in freezer, under -20°C
Refractive Index	1.487

Ethyl 2-chloro-1,3-oxazole-4-carboxylate - Risk and Safety

Hazard Symbols	Xi - Irritant
Hazard Class	IRRITANT

Ethyl 2-chloro-1,3-oxazole-4-carboxylate - Introduction

Ethyl is an organic compound whose chemical formula is C7H6ClNO3. It has the following properties:

1. appearance: ethyl is a colorless to yellowish liquid.

2. Solubility: It has a certain solubility in solvents and can be dissolved in organic solvents such as ethanol, ether and dichloromethane.

3. Melting point and boiling point: The melting point of ethyl l is 48°C to 49°C, and the boiling point is 166°C to 167°C.

4. Vapor pressure: It has a certain vapor pressure, and the vapor pressure at room temperature is about 1 × 10-2 mmHg.

ethyl l is mainly used in the field of drug synthesis and medicine. Its wide range of applications include as an intermediate for anti-infective drugs, an important intermediate for the synthesis of pesticides, and as a raw material for antitumor and antiviral drugs.

From the point of view of preparation, ethyloxazole can be synthesized by reacting 2-chlorooxazole and ethyl chloroformate. In the reaction conditions, the appropriate temperature and reaction time are generally selected, and an appropriate amount of catalyst is added to promote the reaction.

When using ethyl l, pay attention to the following safety information:

1. Avoid skin contact and inhalation: ethyl l is an irritating and toxic chemical substance. Avoid direct contact with skin and inhalation of its vapor.

2. Use protective equipment: Wear appropriate chemical protective gloves, goggles, and protective overalls when handling the compound.

3. storage precautions: ethyl l should be stored in a cool, dry and well-ventilated place, away from fire and flammable materials.

4. Disposal of waste: When disposing of waste, appropriate measures should be taken to dispose of it in accordance with local regulations to avoid adverse effects on the environment and health.

Generally speaking, ethyl l is a compound with important uses in the field of chemical synthesis and medicine, but it is necessary to pay attention to safety during use, and strictly abide by relevant operating regulations and safety measures.

Last Update：2024-04-09 18:58:34